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however, it is not very reactive, but it is the progenitor of many other reactive oxygen species (ROS)

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Luteolin can also increase the expression of antioxidant enzymes such as heme oxygenase-1 (HO-1) via the nuclear factor erythroid 2related factor 2/ antioxidant responsive element (Nrf-2/ARE) complex activation, as it was observed in in vitro models of PD [44, 57] and H 2 O 2 -induced toxicity in in vitro models [5860]

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