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Besides mitochondria, several other cellular organelles likely endoplasmic reticulum (ER), peroxisomes, plasma membrane, cytosol and nucleus with high oxygen consumption serve as endogenous sources to form ROS

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Tyrosine kinase inhibitors in chronic myeloid leukaemia and emergent cardiovascular disease
Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes

Cunha et al., 2020)
