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A wide variety of viral vectors have been employed in clinical applications, including adenovirus, adeno-associated virus, herpes simplex virus, retrovirus, and lentivirus for either in vivo or ex vivo gene therapies (Zhao et al., 2022), with retroviral and lentiviral vectors being exploited for delivering RNA-based payloads (Sung and Kim, 2019)

Factors influencing results include: Injury severity: Minor strains may resolve quickly while chronic degenerative conditions require longer protocols

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Jan 7 2023;doi:10.1007/s11325-022-02770-4

however, the combined application of PE and VD yielded cumulative advantages in terms of insulin sensitivity and hepatic steatosis