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Description
NNT catalyzes hydride transfer from NADH to NADP + , generating NADPH and NAD + , thereby supporting mitochondrial redox balance and ETC function

Step 3: Support the recycling process

Due to the endogenous GSH reduction in pathological state, it is necessary to replenish exogenous L-Glutathione Reduced, Reduced Glutathione

Szabo L, Cummins N, Paganetti P, Odermatt A, Papassotiropoulos A, Karch C et al (2023) ER-mitochondria contacts and cholesterol metabolism are disrupted by disease-associated tau protein

doi: 10.1038/cdd.2015.158
