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Theyre famous for a reason, but GHK-Cu works on a fundamentally different level

While drug expulsion from SLNs is caused by a reduction of amorphous regions in the lipid matrix due to a polymorphic transition from the less-ordered -form to the more-ordered -form, which reduces the space available for drug molecules, the drug is consequently expelled from the lipid core and may migrate to the particle surface or surrounding medium, leading to a gradual decrease in drug loading efficiency over time (Westesen et al., 1997

it can be considered as another limitation of our study

E.Stenkiewicz-WiteskaJ.De MaeyerR

Usually, the needle should be inserted into the skin at 90 degrees (straight up and down, relative to the skin) to ensure that the medication is injected into the fatty tissue