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The copper ion is essential for biological activity the apo-peptide (GHK without copper) shows markedly reduced activity in most assay systems
Cerebrolysin has specific evidence in diabetic neuropathy models

Published studies have investigated NNMT and NNMT inhibitors across areas of laboratory and preclinical research, including NNMT influences multiple interconnected biochemical pathways
10.1016/j.snb.2023.133519 202 YangB.ChoiH.KimS.-H.YoonH

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