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doi: 10.1016/j.canlet.2015.10.010

454 YangZ.QuigleyH.PeaseM.YangY.QianJ.ValentaD.et al (2007)

This rigorous, stratified diagnostic approach is fundamental to differentiating pain mechanisms, guiding appropriate and targeted treatment, and advancing toward a more precise and personalized model of pain medicine

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Fibroblasts and endothelial cells also significantly influence pigmentation, with fibroblasts affecting melanocyte proliferation and pigmentation through MAPK and WNT/-catenin pathways, while endothelial cells stimulate and inhibit pigmentation