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Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics

2021, 118 (45), e2106143118 10.1073/pnas.2106143118

doi: 10.3390/molecules30132883 20 CalvoD

J.BonaguraV.VambutasA

The effects of H 2 O 2 on cell signaling lead to the activation of the inflammasome and the redox-sensitive transcription factors like the inducible hypoxia factor type 1 alpha (HIF-1) and the nuclear factor k (NF-k), with the production of pro-inflammatory cytokines IL-1, IL-6, and TNF- (Mittal et al., 2014)
