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doi: 10.1080/00337577608233050
Drugs Today (Barc) 2011;47:289302

aeruginosa , and Burkholderia fungorum , the oxidation of formaldehyde to formate occurs in a single step that is independent of thiol, pterin, or RuMP (Marx et al., 2004

doi: 10.1038/nrm.2016.80

Interestingly, after Pycnogenol intake, none of the hormone levels showed significant changes compared to baseline or placebo, suggesting non-hormonal mechanisms of Pycnogenol on climacteric symptoms
