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Sigmoidal dose-response curves and reliable estimates of IC 50 values based on non-linear least-squares fitting to the available data could not be obtained since no significant inhibition of DNMT1 and PRMT3 was observed at the tested NNMT inhibitor concentrations (Table 3)

When that framework is missing, even the best-researched combination can underperform or create unnecessary frustration

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SARS-CoV-2 spike-ferritin-nanoparticle adjuvanted with ALFQ induces long-lived plasma cells and cross-neutralizing antibodies
