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Additionally, a notable correlation has been observed between CRGs and various scores related to RNA stemness, DNA stemness, microsatellite instability, and tumor mutational burden [64]

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doi: 10.1176/ajp.152.11.1675 64 ThiblinIPeterssonAGarleM

eNOS palmitoylation influences vascular homeostasis 30 , and PECAM-1 palmitoylation promotes cell surface localization in endothelial cells 31

These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication