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W-DC and Y-DW edited and revised the manuscript

However, dysfunction in this protective mechanism allows the retrograde flow of gastric or gastroduodenal contents into the distal portions of the oesophagus and, in cases of laryngopharyngeal reflux, into the laryngopharynx, oropharynx or even the nasopharynx, triggering the characteristic symptoms of this condition

Pathophysiological aspects of alcohol metabolism in the liver

Therefore, preventing the oxidation of dopamine to adrenochrome may represent a key neuroprotective strategy for safeguarding the aforementioned neurons that are lost in the substantia nigra in PD (Huenchuguala & Segura-Aguilar, 2024b)