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In addition to high-fiber modification of the diet and bulk-forming agents such as psyllium or flaxseed, anticholinergics, analgesics, and antibiotics can be prescribed to manage symptoms

Dosing for fibromyalgia: Standard protocols involve 250-500mcg twice daily via subcutaneous injection

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There are case reports of piriformis syndrome symptoms improving after 10 days of treatment with ultrasound-guided dry-needling

Semaglutide is a prescription medication that works as a GLP-1 receptor agonist and is FDA-approved to treat obesity, type 2 diabetes, metabolic dysfunction-associated steatohepatitis (MASH), and to reduce the risk of chronic kidney disease and major cardiovascular events