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In the ferret model of SARS-CoV infection, a human mAb was found to protect the animals from infection 105
Using this approach, Health Canada (HC 2018) concluded that while the genotoxicity cancer MOA does not meet the modified Bradford hill criteria, the regenerative proliferation cancer MOA meets many of these criteria (specifically dose and temporal concordance, consistency, analogy, and biological concordance). This conclusion led Health Canada (HC 2018) to adopt a threshold model (rather than a linear low-dose extrapolation model) for evaluating cancer risks associated with 1,4-dioxane that is directly linked to the saturation of 1,4-dioxanes metabolic pathways

Brain Res 6:6094 Scheibel ME, Lindsay RD, Tomiyasu U et al (1976) Progressive dendritic changes in the aging human limbic system

A: Unlike NSAIDs, BPC-157 does not appear to damage the GI tract
