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Type II has a deletion in position 358 of T in exon 4, and Type III has an insert in position 138GA of exon 2

GPx4 also affects metabolic diseases, such as NAFLD (non-alcoholic fatty liver disease), where cGPx4 protein expression is down-regulated and induces the non-classical transcriptional variant iGPx4, which promotes ferroptosis by interacting with cGPx4 and converting it from an active monomer to an inactive oligomer, and OSA (obstructive sleep apnea), where macrophage-secreted IL6 promotes hepatocyte MARCH3 expression, mediates GPx4 ubiquitination degradation and exacerbates ferroptosis and lipid accumulation

What supplements should you take to deal with this CBS gene mutation, as it is incorrectly referred to on the media by influencers like Gary Brecka

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