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Likewise, for a similar H 2 O 2 intracellular concentration of 0.12 M in the trx3 and trx1 strains, the oxidation of OxyR is much higher in the trx1 strain (89%) than in the trx3 strain (24%)

Zhang Z, Yung KK, Ko JK

doi: 10.1097/WOX.0B013E3182439613 11 JopkiewiczS

The described compounds are hence distinct from monovalent degraders and bivalent PROTACs described to date, which typically recruit a single E3 ligase substrate receptor for target degradation

ABR waves were recorded in each animal before starting the drug treatments (baseline hearing threshold), then 3 weeks later at the end of the experiment (Fig
