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The ratio of reduced to oxidized glutathione serves as a key indicator of the cellular redox potential, with even small changes in the GSH:GSSG ratio influencing protein function by altering cysteine oxidation and disulfide bond formation ( de novo synthesis, GSH degradation and metabolism, the uptake and export of GSH and GSSG and the efficient reduction of GSSG

doi: 10.1519/1533-4287(2003)017 2.0.co;2

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[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Scott C., Neira Agonh D., Lehmann C

However, to truly appreciate the benefits of this therapy, one must understand the complex biochemistry that occurs beneath the surface