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64 Positive effects of B12, 2500 g daily sublingually for 90 days (form not reported), have also been seen in musculoskeletal pain as a side-effect of aromatase inhibitors in patients with breast cancer, with a 34% reduction of pain

The safety data for each compound individually is reassuring, but combination safety requires its own evaluation because pharmacological interactions can produce unexpected results even when each agent is well-characterized on its own

Additionally, the elderly population may have decreased absorption or utilization of dietary vitamin B6, making supplementation a viable option

A standard 1ml syringe with a 2729g needle works well

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