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Protein- protein docking and molecular dynamics simulation of wild and mutant GSTP1- JNK complex Protein-protein interaction between JNK with wild-type GSTP1 showed high affinity (850.18 Kcal/mol) than mutant GSTP1 (757.79) Table 3

These drugs can induce apoptosis and disrupt cellular homeostasis, leading to irreversible SHL

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Cells were left to adhere for 90 min at room temperature followed by an overnight incubation at 37 C, 5% CO 2

Resazurin is a blue dye that is internalized by cells and metabolically reduced by diaphorase activity enzymes to the highly fluorescent pink compound resorufin