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Nitisinone increases melanin in people with albinism Wednesday, February 20, 2019 Nitisinone increases melanin in people with albinism A small pilot clinical study at the National Eye Institute (NEI) suggests that the drug nitisinone increases melanin production in some people with oculocutaneous albinism type 1B (OCA-1B), a rare genetic disease that causes pale skin and hair and poor vision