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Furthermore, tPA intervention increased brain matrix metalloproteinase (MMP-9) (Yang et al., 2016), as well as phosphorylation of connexin43, a gap junction protein contributing to blood brain barrier permeability and hemorrhagic transformation (Tang and Han, 2013)

Astrocytes are involved in numerous neurodegenerative disorders and can significantly influence depression

The inherent multidrug resistance induced resistance to macrolides and disparities between in vitro drug sensitivity testing and clinical responses all contribute to the complexity of treatment
Cryopreservation of rat, dog and human hepatocytes: influence of preculture and cryoprotectants on recovery, cytochrome P450 activities and induction upon thawing

Titze J, Luft FC
