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Pharmacological evidence for N-methyl-D-aspartate receptors on nigrostriatal dopaminergic terminals

Focus on appetite regulation and metabolic adaptation
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The proposed reason the combination is more than the sum of its parts is that amylin agonism appears to sensitize hypothalamic leptin signaling

MK-677 has therapeutic potential for the following people: The elderly: MK-677 is being studied as a potential treatment for sarcopenia (muscle wasting) and frailty
