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Research in rodents indicates that apart from the activation of MMP2, the peptide might also activate fibroblasts, which produce and maintain MMP2 and other components of the extracellular matrix, such as collagen and elastin

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Although not directly associated with all opacities, coloration or brunescence is also quantified, since brunescence diminishes visual function

ACAA and EHHADH are essential proteins in the fatty acid -oxidation (FAO) process, and their downregulation is associated with decreased efficiency