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In anemia, tissues receive less oxygen, causing fatigue and weakness

Other symptoms related to Vitamin B-12 deficiency are weight loss, loss of hearing, anemia, loss of appetite

[6] The nutritional deficiencies associated with aphthous stomatitis (vitamin B12, folate, and iron) can all cause a decrease in the thickness of the oral mucosa (atrophy)

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(6) The results suggest that conversion to oral supplements in the first year was considerably more expensive than intramuscular injections as a result of closer monitoring of those on oral supplements during the first year