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A study involving 331 AIDS patients found that when patients received supplements including various carotenoids (natural pigments with antioxidant properties), as well as multivitamins and minerals, mortality rates were lower, and CD4 T-cell counts were higher, compared with patients who received the same supplementation without the carotenoids

Chem Pharm Bull (Tokyo) 48(5):651656 Biswas NR et al (1996) Comparative double blind multicentric randomised placebo controlled clinical trial of a herbal preparation of eye drops in some ocular ailments

Similarly, the elderly, with reduced GH or IGF-1 signals show poor response to immune stimuli [141]

On further analysis, we found that the high-grade serous ovarian cancer cell lines used have high expression of CCNE1 (encoding cyclin E1)

Beisswenger PJ, Drummond KS, Nelson RG, Howell SK, Szwergold BS, Mauer M