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GHK-Cu (glycyl-L-histidyl-L-lysine-copper) is a naturally occurring tripeptide - three amino acids bound to a copper ion

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In the clinical trial (NCT05859997), three patients with therapy-resistant autoimmune diseasesincluding immune-mediated necrotizing myopathy (IMNM) and diffuse cutaneous systemic sclerosis (SSc)showed a reduction in disease markers and improved quality of life over six months, with no severe side effects such as cytokine release syndrome or graft-versus-host disease (GvHD)