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First, the direct interaction between GSH and the active site of tyrosinase, resulting in the activation of tyrosinase activity when the concentrations of GSH is below 3 mM and inhibition at higher GSH concentrations [82]

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The anti-inflammatory properties of glutathione can also help calm irritated skin and reduce redness, making it particularly beneficial for those dealing with post-inflammatory hyperpigmentation from acne or other skin concerns

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