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During the progression of MASH, the accumulation of lipotoxic and reactive oxygen species induce hepatocellular injury, inflammasome activation, release of proinflammatory chemokines with subsequent monocyte infiltration and activation of macrophages and hepatic stellate cells that drive steatohepatitis and hepatic fibrosis 2,3,4

doi: 10.1016/j.rmed.2017.09.003 135 ChopraANautiyalAKalkanisAJudsonMA

Right versus left colon cancer biology: integrating the consensus molecular subtypes

As glycocalyx degradation results in endothelial dysfunction, investigators have explored the role of glycocalyx degradation as a central contributor to the development of CVD associated with diabetes

Incidence, Clinical Characteristics, and Prognostic Significance Of Chromosome 3q Abnormalities In Patients With CML Blast Phase