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Description
XBP1s up-regulates genes that expand ER quality-control and degradation machinery, whereas XBP1u acts as a brake, repressing this transcriptional response (100)

Anthracyclines such as doxorubicin and epirubicin cause cell death and cytotoxicity by intercalating into DNA and disrupting replication, this is part of standard treatment (67, 215)

People receive infused biologics through a vein in the hospital, doctors office, or infusion center

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