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The role of substance P in stress and anxiety responses
31 Ejaculatory problems, such as retrograde ejaculation, premature ejaculation, delayed ejaculation (difficulty or inability to achieve ejaculation), and anejaculation (absence of ejaculation), can be underlying factors in male infertility

As opposed to the Morris Water Maze, the Dry Morris Water Maze is relatively less stressful for the subject as it doesnt use an aversive stimulus (fear of drowning in MWM)

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The primary effect will be loss of the metabolic rate enhancement, though tirzepatide's appetite suppression remains intact