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Conclusion: Under tightly controlled dietary conditions, a single dose of pomegranate extract did not reduce post-OCC TMAO responses in the overall cohort

At the initial baseline visit, serial venous sampling performed after oral d 3 -l-carnitine challenge revealed rapid increases in plasma concentrations of d 3 -l-carnitine, and subsequent increases in d 3 -BB and d 3 -TMAO following a lag phase (Figure 1, AC, filled circles)

Current recordings were all leak-subtracted and cells with leak currents above 100 pA were discarded

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Glycerophospholipid and sphingolipid analysis was performed following a worm-adapted version of a previously published method 66,68