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Using in vitro cell-based assays, the researchers found that while both peptides activated the amylin and calcitonin receptors, KBP-336 was more potent and showed a bias towards the calcitonin receptor compared to cagrilintide
Even absent these logistical hurdles, pharmaceutical companies might not want to invest in clinical trials

Kyowa Hakko Bio Co., Ltd

doi: 10.1016/j.apsb.2021.09.023 24
Nat Rev Cancer 23(2):7894
