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Description
Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimers disease

11 A great deal of effort has been focused on the development of small molecules to inhibit checkpoint response proteins, such as Chk1, with the idea that they would inhibit radiation-induced G2 arrest and perhaps repair and thus be used as radiation sensitizers

Unfortunately, this ignores imaging data regarding biodistribution of the administered agents, target engagement by the agent, immune system activation, and other critical imaging biomarkers that may precede or predict an objective radiologic response in terms of tumor size

3.1 SCOPE

Nov-Dec 2015;29(8):1295-303
