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To KK, Leung WW, Ng SS

Subsequently, inflammation and oxidative stress in the brain tissue, in turn, amplify the extent of BBB disruption, which creates a vicious cycle that would fuel the generation and progression of SAE

The underlying causes of this deficiency are not fully understood but appear to be multifactorial

ALZHEIMER DISEASE 3.1
Polygenic influence on plasma homocysteine: association of two prevalent mutations, the 844ins68 of cystathionine -synthase and A(2756)G of methionine synthase, with lowered plasma homocysteine levels
