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Weight loss was an adverse effect associated with zonisamide treatment in clinical trials for epilepsy
Vitamin B12 use while breastfeeding

Kulcenty, K., Holysz, M

There are no other absolute contraindications reported for hydroxocobalamin use in deficiency states, but caution is advised in individuals with conditions such as early Lebers optic neuropathy (a rare hereditary optic atrophy) due to the theoretical risk of worsening vision
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Spontaneous murine lupus-like syndromes
