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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88

In tendon and ligament pathology, both peptides have shown remarkable efficacy in preclinical models of tissue repair

Typically, taking 1,000 IU per 25 lbs

These actions enhance cell proliferation and migration, promote new blood vessel formation ( angiogenesis ), and accelerate wound closure in injured tissues

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