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However, regardless of this is the isoform with the highest sensitivity to citrate in normal tissues 178 , phosphofructokinase-1 in tumors exhibits reduced sensitivity to citrate, accompanied by increased sensitivity to activation by fructose-1,-6-bisphosphate 179,180,181

As a result, the combined treatment demonstrates a markedly improved antagonistic effect against I/R-induced oxidative stress (Huang et al., 2014)

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Cervical radiculopathy may sometimes be accompanied by shock-like pain

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