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Furthermore, selenium deficiency has been shown to predict prolonged ICU stays, higher infection rates, and increased hospital costs, underscoring its clinical and economic implications in critical care [4,6,11,52]

As the score did not significantly differ between HC and CC individuals, the two control groups were combined as a single group (others) for final analysis

The mechanisms driving central sensitization include elevated substance P, reduced descending pain inhibition, altered glutamate signaling, and microglial activation in the central nervous system

doi: 10.1089/sur.2017.089

At the same time, many antioxidants are being tested in clinical trials for the first time, and there is no additional evidence to support their efficacy
