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while HGF was first isolated from the liver [51] and has now been identified in the brain [52-54]

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Research has investigated its role as a major antioxidant, electrophile scavenger and substrate for glutathione peroxidase and glutathione S-transferase enzymes in oxidative stress and detoxification pathways
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In a systematic review and meta-analysis (17 studies, n=1342) including seven NP conditions, only third-tier evidence (obtained from well-designed controlled trials without randomization) was available, and only 2 trials determined amitriptyline was more efficacious than placebo
