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When 4-ClDzp was added to the perfusate, hearts were protected against arrhythmias induced by diamide (Figure 2C) and the arrhythmia scores were significantly lower than in hearts that received diamide alone (Figure 3)

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One such model was the fluid percussion injury (FPI) used in cats (Sullivan et al., 1976), with its subsequent use in dogs, and sheep (Millen et al., 1985), swine (Solomon et al., 2011), as well as rabbits (Hrtl et al., 1997) and finally rodents (Dixon et al., 1987

Alpha4beta2 nicotinic acetylcholine receptor activation ameliorates impairment of spontaneous alternation behavior in stroke-prone spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder