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Description
NICE guidelines recommend hydroxocobalamin 1 mg intramuscularly three times weekly for 2 weeks (without neurological involvement) or on alternate days until no further improvement (with neurological symptoms)
doi: 10.1038/nature05127
The default is ethics-led clearance with regulatory notification
Therefore, it would be difficult to predict the degree of improvement prior to GH treatment using pretreatment IGF-1
