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Published on: April 19, 2005

427: Folic Acid and Multivitamin Supplementation for Prevention of Folic Acid-Sensitive Congenital Anomalies for more information

The authors suggest that either methyl-B12 and adenosyl-B12 should be given together, or either cyano-B12 or hydroxo-B12 on their own, both of which can be converted into both active forms

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Additionally, insulin deficiency decreases the expression of a number of genes necessary for target tissues to respond normally to insulin such as glucokinase in liver and the GLUT4 class of glucose transporters in adipose tissue and skeletal muscle