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adhC and estD displayed an enhanced sensitivity to growth inhibition by exogenous formaldehyde but not other aldehydes or carbonyl compounds such as methylglyoxal ( estD mutant when compared with the adhC single mutant or the adhC-estD double mutant

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization

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Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence

Additionally, ALA sensitized NSCLC cells to apoptosis by downregulating the expression of PDK1, leading to a reduction in NRF2 levels and an enrichment of mitochondrial ROS [49]