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Xu Z., Ren F., Wang P., et al., A Generative AIDiscovered TNIK Inhibitor for Idiopathic Pulmonary Fibrosis: A Randomized Phase 2a Trial, Nature Medicine 31 (2025): 26022610

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In the living liver tissue, there is substance transport and signal transduction between hepatocytes and the ECM and the ECM also plays a role in supporting the three-dimensional structure (209)