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The project revealed a novel mechanism by which RanBPM regulates p21 protein stability, and plays a critical role in the regulation of DDR, thereby suggesting that it might be a promising therapeutic strategy to develop small molecular compounds destroying the protein interaction between RanBPM and p21

Progress toward acetate supplementation therapy for Canavan disease: glyceryl triacetate administration increases acetate, but not N-acetylaspartate, levels in brain

Performance of molecular classification in predicting oncologic outcomes of fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer

It is reported that the GSH system plays an important role in maintaining redox homeostasis and thus supports cancer cells' survival in response to oxidative stress [29]

Protein malabsorption can lead to severe weight loss, muscle wasting, and hypoalbuminemia, manifesting clinically as peripheral edema