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doi: 10.1016/j.anai.2017.02.014

With respect to the biological pathway, there is consistent evidence for the mitogenic role of IGF1 in carcinogenesis by increasing cell proliferation and inhibiting apoptosis

Finally, it was recently suggested that IGF-I has significant characteristics to be a good marker for the insulin resistance syndrome and risk of cardiovascular disease, since logistic regression analysis showed that each unit increase in log-transformed IGF-I concentrations was associated with a 90.5% reduction in the risk of metabolic syndrome [274]

Various activation signals, including mediators of diseases, change the expression of MTs, enabling regulation of zinc homeostasis in the long term as well [80,104]

Amin M, Hadi M, Jafari E (2023) Opennano niosome nanocarrier enhances the ameliorating effects of myrtenol in the lungs of rats with experimental asthma