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Implications for pharmacology and therapeutics of Parkinson disease and related disorders

GPX4 volume density is increased from 0.0018 0.0002 in controls (n = 11) to 0.0038 0.0007 in PD (n = 12) (P = 0.0192), indicating that GPX4 is either upregulated in surviving neurons or that a greater percentage of cells not expressing GPX4 are lost compared to cells with GPX4

Toxins-antitoxins: diversity, evolution and function

Another cause - granted, identified as rare - is a B12 deficiency

has been shown to alleviate oxidative stress-induced injury in the human retinal pigment epithelial (ARPE-19) cells via the PI3K/Akt-Nrf2 signaling pathway