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Description
Mice in the vehicle cohort received three subcutaneous (SC) saline (1 ml/kg) injections/day (~0930, 1330, 1730 h) and mice in the treatment cohort received three SC injections of the NNMT inhibitor 5-amino-1MQ at a dose of 20 mg/kg/injection for a total dose of ~34 mg/kg/day of the parent compound (calculated according to free weight) for 11 days
Recent literature has expanded the application bracket through novel research streams
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Units on a U-100 syringe: 0.045 mL 100 = 4.5 units (round to the ~45 unit mark on the barrel)
Nicotinamide N-Methyltransferase: A Novel Regulator of Metabolic Homeostasis. Trends in Endocrinology & Metabolism , 28(5), 340-353.
