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doi: 10.1097/WAD.0000000000000345 149 RiedelG.KangS

Monitoring Progress Effectively: Rather than relying solely on scale weight, which can be misleading due to muscle preservation and fluid fluctuations, comprehensive progress tracking should include body composition analysis (DEXA scan, bioelectrical impedance, or skinfold measurements), circumference measurements (waist, hips, thighs, arms), progress photos taken in consistent lighting and positioning, and subjective measures like energy levels, appetite patterns, and how clothing fits

UTR2, the 5untranslated region of the SHMT2 transcript

Ceramide accumulation in muscle and adipose tissue has been long proposed to drive insulin resistance [54], and ceramides can induce Golgi fragmentation and block ER-to-Golgi transport [55]