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Malfunctioning phagocytosis impairs the killing of bacteria that reach the lamina propria through the permeable epithelial barrier, which results in excessive Toll-like receptor stimulation, proinflammatory cytokine secretions, and activation of acquired immune responses, all of which significantly raise intestinal inflammatory reactions in genetically susceptible individuals who harbor mutations in the IBD-susceptibility gene(s) (Duboc et al., 2013)

Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach

Preferably, compositions of the present invention comprising an L-carnitine calcium salt of an organic acid of the present invention are administered substantially contemporaneously with other drug treatments or as a combination composition containing a mixture with other drug treatments

Int J Obes Relat Metab Disord 26 , 590592

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